Take a look at the sticky topics in the various fora, they provide essential information.
Information on how to use Comskip in combination with various PVR softwares can be found here:
- SageTV: http://www.geektonic.com/2008/02/skip-c ... utton.html
MCE: http://cybernetnews.com/2008/01/28/cybe ... ia-center/
MediaPortal: http://forum.team-mediaportal.com/tips- ... rtal-5280/
BeyondTV: http://www.geektonic.com/2008/03/how-to ... mskip.html
Mac OSX: http://code.google.com/p/etv-comskip/